cmake_minimum_required(VERSION 3.9)

option(WITH_HDF5 "Build with HDF5" OFF)
if(WITH_HDF5)
  list(APPEND VCPKG_MANIFEST_FEATURES "hdf5")
endif()
option(WITH_MATLAB "Build Matlab wrappers" OFF)
if(WITH_MATLAB)
  list(APPEND VCPKG_MANIFEST_FEATURES "matlab")
endif()
option(WITH_PYTHON "Build Python module" OFF)
if(WITH_PYTHON)
  list(APPEND VCPKG_MANIFEST_FEATURES "python")
endif()
option(BUILD_TESTING "Build the testing tree." ON)
if(BUILD_TESTING)
  list(APPEND VCPKG_MANIFEST_FEATURES "tests")
endif()

project(...)

include(CTest)
enable_testing()

...